Teneligliptin Exerts Antinociceptive Effects in Rat Model of Partial Sciatic Nerve Transection Induced Neuropathic Pain

Teneligliptin Exerts Antinociceptive Effects in Rat Model of Partial Sciatic Nerve Transection Induced Neuropathic Pain

Neuropathic pain (NP), is a chronic pain resulting from nerve injury, with limited treatment options. Teneligliptin (TEN) is a dipeptidyl peptidase-4 inhibitor (DPP-4i) approved to treat type 2 diabetes. DPP-4is prevent the degradation of the incretin hormone glucagon-like peptide 1 (GLP-1) and prol...

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Bibliographic Details
Main Authors: Yaswanth Kuthati, Vaikar Navakanth Rao, Prabhakar Busa, Chih-Shung Wong
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antioxidants
Subjects:
neuropathic pain
partial sciatic nerve transection
dipeptidyl peptidase-4 inhibitor
teneligliptin
glucagon-like peptide 1
glial fibrillary acidic protein
Online Access:https://www.mdpi.com/2076-3921/10/9/1438

Internet

https://www.mdpi.com/2076-3921/10/9/1438

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