Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway

Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway

Abstract Background Hepatic ischemia/reperfusion (I/R) injury can be a major complication following liver surgery contributing to post-operative liver dysfunction. Maresin 1 (MaR1), a pro-resolving lipid mediator, has been shown to suppress I/R injury. However, the mechanisms that account for the pr...

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Bibliographic Details
Main Authors: Da Tang, Guang Fu, Wenbo Li, Ping Sun, Patricia A. Loughran, Meihong Deng, Melanie J. Scott, Timothy R. Billiar
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Molecular Medicine
Subjects:
Lipid mediators
Hepatic ischemia/reperfusion
Hepatocytes
Inflammation
Oxidative stress
Apoptosis
Online Access:https://doi.org/10.1186/s10020-021-00280-9

Internet

https://doi.org/10.1186/s10020-021-00280-9

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