The effect of luseogliflozin on bone microarchitecture in older patients with type 2 diabetes: study protocol for a randomized controlled pilot trial using second-generation, high-resolution, peripheral quantitative computed tomography (HR-pQCT)

The effect of luseogliflozin on bone microarchitecture in older patients with type 2 diabetes: study protocol for a randomized controlled pilot trial using second-generation, high-resolution, peripheral quantitative computed tomography (HR-pQCT)

Abstract Background Older patients with type 2 diabetes mellitus (T2DM) have an increased risk of bone fracture independent of their bone mineral density (BMD), which is explained mainly by the deteriorated bone quality in T2DM compared to that in non-diabetic adults. Sodium-glucose co-transporter (...

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Bibliographic Details
Main Authors: Ai Haraguchi, Riyoko Shigeno, Ichiro Horie, Shimpei Morimoto, Ayako Ito, Ko Chiba, Yurika Kawazoe, Shigeki Tashiro, Junya Miyamoto, Shuntaro Sato, Hiroshi Yamamoto, Makoto Osaki, Atsushi Kawakami, Norio Abiru
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Trials
Subjects:
Type 2 diabetes
Luseogliflozin
SGLT2 inhibitor
HR-pQCT
Fracture
Bone
Online Access:http://link.springer.com/article/10.1186/s13063-020-04276-4

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http://link.springer.com/article/10.1186/s13063-020-04276-4

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