Oleanolic Acid Acetate Exerts Anti-Inflammatory Activity via IKKα/β Suppression in TLR3-Mediated NF-κB Activation

Oleanolic acid acetate (OAA), a major triterpenoid compound of <i>Vigna angularis</i> (azuki bean, <i>V. angularis</i>), has been shown to downregulate inflammatory responses in macrophages. Here, we show the molecular basis for the effect of OAA on Toll-like receptor (TLR) d...

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Bibliographic Details
Main Authors: Hyung Jin Lim, Hyun-Jae Jang, Mi Hwa Kim, Soyoung Lee, Seung Woong Lee, Seung-Jae Lee, Mun-Chual Rho
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/21/4002