Differential gene expression between wild-type and Gulo-deficient mice supplied with vitamin C

Differential gene expression between wild-type and Gulo-deficient mice supplied with vitamin C

The aim of this study was to test the hypothesis that hepatic vitamin C (VC) levels in VC deficient mice rescued with high doses of VC supplements still do not reach the optimal levels present in wild-type mice. For this, we used a mouse scurvy model (sfx) in which the L-gulonolactone oxidase gene (...

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Bibliographic Details
Main Authors: Yan Jiao, Jifei Zhang, Jian Yan, John Stuart, Griffin Gibson, Lu Lu, Robert Willaims, Yong Jun Wang, Weikuan Gu
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2011-01-01
Series:Genetics and Molecular Biology
Subjects:
gene expression
L-gulonolactone oxidase
liver
oxidative stress
vitamin C
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000300004

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000300004

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