DOCLASP - Docking ligands to target proteins using spatial and electrostatic congruence extracted from a known holoenzyme and applying simple geometrical transformations [version 3; referees: 2 approved]
The ability to accurately and effectively predict the interaction between proteins and small drug-like compounds has long intrigued researchers for pedagogic, humanitarian and economic reasons. Protein docking methods (AutoDock, GOLD, DOCK, FlexX and Glide to name a few) rank a large number of possi...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2016-06-01
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| Series: | F1000Research |
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| Online Access: | http://f1000research.com/articles/3-262/v3 |