Discovering cooperative relationships of chromatin modifications in human T cells based on a proposed closeness measure.

BACKGROUND: Eukaryotic transcription is accompanied by combinatorial chromatin modifications that serve as functional epigenetic markers. Composition of chromatin modifications specifies histone codes that regulate the associated gene. Discovering novel chromatin regulatory relationships are of gene...

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Bibliographic Details
Main Authors: Jie Lv, Hong Qiao, Hongbo Liu, Xueting Wu, Jiang Zhu, Jianzhong Su, Fang Wang, Ying Cui, Yan Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2997069?pdf=render