Role of MCP-1 and CCR2 in ethanol-induced neuroinflammation and neurodegeneration in the developing brain

Role of MCP-1 and CCR2 in ethanol-induced neuroinflammation and neurodegeneration in the developing brain

Abstract Background Neuroinflammation and microglial activation have been implicated in both alcohol use disorders (AUD) and fetal alcohol spectrum disorders (FASD). Chemokine monocyte chemoattractant protein 1 (MCP-1) and its receptor C-C chemokine receptor type 2 (CCR2) are critical mediators of n...

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Bibliographic Details
Main Authors: Kai Zhang, Haiping Wang, Mei Xu, Jacqueline A. Frank, Jia Luo
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Neuroinflammation
Subjects:
Alcohol abuse
Apoptosis
Chemokines
Development
Glia
Neurodegeneration
Online Access:http://link.springer.com/article/10.1186/s12974-018-1241-2

Internet

http://link.springer.com/article/10.1186/s12974-018-1241-2

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