Homocysteine mediates transcriptional changes of the inflammatory pathway signature genes in human retinal pigment epithelial cells

Homocysteine mediates transcriptional changes of the inflammatory pathway signature genes in human retinal pigment epithelial cells

AIM: To test whether homocysteine (Hcy) can influence the transcriptional profile, we hypothesized that Hcy can lead to the induction of proinflammatory molecules in the retinal cells of aging people. METHODS: An unbiased in vitro inflammatory pathway focused study was designed employing retinal pi...

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Bibliographic Details
Main Authors:	Mahavir Singh, Suresh C Tyagi
Format:	Article
Language:	English
Published:	Press of International Journal of Ophthalmology (IJO PRESS) 2017-05-01
Series:	International Journal of Ophthalmology
Subjects:	704 chemokine choroidal neovascularization cytokine gene expression hyperhomocysteinemia inflammation macular degeneration retinal remodeling
Online Access:	http://www.ijo.cn/en_publish/2017/5/20170506.pdf

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