Homocysteine mediates transcriptional changes of the inflammatory pathway signature genes in human retinal pigment epithelial cells

AIM: To test whether homocysteine (Hcy) can influence the transcriptional profile, we hypothesized that Hcy can lead to the induction of proinflammatory molecules in the retinal cells of aging people. METHODS: An unbiased in vitro inflammatory pathway focused study was designed employing retinal pi...

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Bibliographic Details
Main Authors: Mahavir Singh, Suresh C Tyagi
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2017-05-01
Series:International Journal of Ophthalmology
Subjects:
704
Online Access:http://www.ijo.cn/en_publish/2017/5/20170506.pdf