All-Trans Retinoic Acid Fosters the Multifarious U87MG Cell Line as a Model of Glioblastoma

Glioblastoma multiforme (GBM) is a primary brain cancer of poor prognosis, with existing treatments remaining essentially palliative. Current GBM therapy fails due to rapid reappearance of the heterogeneous neoplasm, with models suggesting that the recurrent growth is from treatment-resistant gliobl...

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Bibliographic Details
Main Authors: Markéta Pokorná, Michael Hudec, Iva Juříčková, Michael Vácha, Zdeňka Polívková, Viera Kútna, Jan Pala, Saak V. Ovsepian, Marie Černá, Valerie Bríd O’Leary
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/11/6/812