Role of e2/e3/e4 allelic polymorphism of apoli-poprotein E in regulation of lipid profile in Caucasian population of Eastern Siberia

We determined three isoforms of APOEprotein differing by amino acid residues in 112 and 158 positions: aroE2 (112Cys, 158Cys), apoE3 (112Cys, 158Arg) and aroE4 (112Arg, 158Arg). Protein isoforms differed in the degree of effectiveness of protein interaction with the liver cell receptors during chole...

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Bibliographic Details
Main Authors: O. V. Kalyuzhnaya, T. A. Bairova, L. V. Rychkova, L. I. Kolesnikova
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2016-05-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/208