The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells.

Bone marrow hematopoietic stem cells (HSCs) balance proliferation and differentiation by integrating complex transcriptional and post-translational mechanisms regulated by cell intrinsic and extrinsic factors. We found that transcripts of G(0)/G(1) switch gene 2 (G0S2) are enriched in lineage(-) Sca...

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Bibliographic Details
Main Authors: Takeshi Yamada, Chun Shik Park, Audrea Burns, Daisuke Nakada, H Daniel Lacorazza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3365016?pdf=render