Open questions: CRISPR biology

Abstract CRISPR-Cas systems, the purveyors of adaptive immunity in archaea and bacteria and sources of the new generation of genome engineering tools, have been studied in exquisite molecular detail. However, when it comes to biological functions, ecology, and evolution of CRISPR-Cas, many more intr...

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Bibliographic Details
Main Author: Eugene V. Koonin
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Biology
Online Access:http://link.springer.com/article/10.1186/s12915-018-0565-9