Analysis of factor V Leiden and prothrombin mutations in patients with suspected thrombophilia in São Paulo state-Brazil

INTRODUCTION: Prothrombin (factor II) is a thrombin precursor, which induces fibrin formation. A mutation in the prothrombin gene (G20210A) has been described, which is directly associated with high prothrombin levels, hence thrombophilia. G1691A mutation in the factor V Leiden (FVL) gene occurs on...

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Bibliographic Details
Main Authors: Marcos Edgar Herkenhoff, Rodrigo Gaulke, Vanessa Rosália Remualdo, Carlos André da Veiga Lima Rosa
Format: Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2013-06-01
Series:Jornal Brasileiro de Patologia e Medicina Laboratorial
Subjects:
SNP
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000300003&lng=en&tlng=en