Analysis of factor V Leiden and prothrombin mutations in patients with suspected thrombophilia in São Paulo state-Brazil
INTRODUCTION: Prothrombin (factor II) is a thrombin precursor, which induces fibrin formation. A mutation in the prothrombin gene (G20210A) has been described, which is directly associated with high prothrombin levels, hence thrombophilia. G1691A mutation in the factor V Leiden (FVL) gene occurs on...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Sociedade Brasileira de Patologia Clínica
2013-06-01
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Series: | Jornal Brasileiro de Patologia e Medicina Laboratorial |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000300003&lng=en&tlng=en |