Preliminary Biological Evaluation of 18F-FBEM-Cys-Annexin V a Novel Apoptosis Imaging Agent

A novel annexin V derivative (Cys-Annexin V) with a single cysteine residue at its C-terminal has been developed and successfully labeled site-specifically with 18F-FBEM. 18F-FBEM was synthesized by coupling 18F-fluorobenzoic acid (18F-FBA) with N-(2-aminoethyl)maleimide using optimized reaction c...

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Bibliographic Details
Main Authors: Chunxiong Lu, Quanfu Jiang, Minjin Hu, Cheng Tan, Huixin Yu, Zichun Hua
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/3/4902