Decreased muscle‐derived musclin by chronic resistance exercise is associated with improved insulin resistance in rats with type 2 diabetes

Abstract Chronic resistance exercise induces improved hyperglycemia in patients with type 2 diabetes mellitus. Musclin, a muscle‐derived secretory factor, is involved in the induction of insulin resistance via the downregulation of the glucose transporter‐4 (GLUT‐4) signaling pathway in skeletal mus...

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Bibliographic Details
Main Authors: Mio Shimomura, Naoki Horii, Shumpei Fujie, Kenichiro Inoue, Natsuki Hasegawa, Keiko Iemitsu, Masataka Uchida, Motoyuki Iemitsu
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14823