Review of applications of CRISPR-Cas9 gene-editing technology in cancer research

Abstract Characterized by multiple complex mutations, including activation by oncogenes and inhibition by tumor suppressors, cancer is one of the leading causes of death. Application of CRISPR-Cas9 gene-editing technology in cancer research has aroused great interest, promoting the exploration of th...

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Bibliographic Details
Main Authors: Ziyi Zhao, Chenxi Li, Fei Tong, Jingkuang Deng, Guofu Huang, Yi Sang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Biological Procedures Online
Subjects:
Online Access:https://doi.org/10.1186/s12575-021-00151-x