The Drosophila MCPH1-B isoform is a substrate of the APCCdh1 E3 ubiquitin ligase complex

The Anaphase-Promoting Complex (APC) is a multi-subunit E3 ubiquitin ligase that coordinates progression through the cell cycle by temporally and spatially promoting the degradation of key proteins. Many of these targeted proteins have been shown to play important roles in regulating orderly progres...

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Bibliographic Details
Main Authors: Sarah G. Hainline, Jamie L. Rickmyre, Leif R. Neitzel, Laura A. Lee, Ethan Lee
Format: Article
Language:English
Published: The Company of Biologists 2014-06-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/3/7/669