Quantifying cell transitions in C. elegans with data-fitted landscape models.

Increasing interest has emerged in new mathematical approaches that simplify the study of complex differentiation processes by formalizing Waddington's landscape metaphor. However, a rational method to build these landscape models remains an open problem. Here we study vulval development in C....

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Bibliographic Details
Main Authors: Elena Camacho-Aguilar, Aryeh Warmflash, David A Rand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1009034