LncRNA HCP5 Induces Gastric Cancer Cell Proliferation, Invasion, and EMT Processes Through the miR-186-5p/WNT5A Axis Under Hypoxia

LncRNA HCP5 Induces Gastric Cancer Cell Proliferation, Invasion, and EMT Processes Through the miR-186-5p/WNT5A Axis Under Hypoxia

ObjectiveTo experimentally determine the involvement and mechanism of long non-coding RNA (lncRNA) HCP5 in the development of gastric cancer (GC).MethodsDetection of HCP5, miR-186-5p, and WNT5A expression in clinical GC tissues and adjacent healthy tissues was performed, followed by Pearson correlat...

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Bibliographic Details
Main Authors: Ming Gao, Liying Liu, Yudan Yang, Mengyi Li, Qingqing Ma, Zhiwei Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
hypoxia
gastric cancer
lncRNA HCP5
miR-186-5p
WNT5A
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.663654/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.663654/full

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