Downregulation of long noncoding RNA HCP5 contributes to cisplatin resistance in human triple-negative breast cancer via regulation of PTEN expression

Downregulation of long noncoding RNA HCP5 contributes to cisplatin resistance in human triple-negative breast cancer via regulation of PTEN expression

Background: Abnormally expressed long non-coding RNA (lncRNA) is associated with the development of breast cancer and multidrug resistance. However, the molecular mechanism by which lncRNA regulates cisplatin (DDP) in triple-negative breast cancer (TNBC) remains unclear. Methods: DDP resistant cell...

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Bibliographic Details
Main Authors: Jingjing Wu, Hao Chen, Meina Ye, Bing Wang, Yuzhu Zhang, Jiayu Sheng, Tian Meng, Hongfeng Chen
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
HCP5
Cisplatin resistance
Triple-Negative breast cancer
PTEN
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219301179

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http://www.sciencedirect.com/science/article/pii/S0753332219301179

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