C. elegans orthologs MUT-7/CeWRN-1 of Werner syndrome protein regulate neuronal plasticity

C. elegans orthologs MUT-7/CeWRN-1 of Werner syndrome protein regulate neuronal plasticity

Caenorhabditis elegans expresses human Werner syndrome protein (WRN) orthologs as two distinct proteins: MUT-7, with a 3′−5′ exonuclease domain, and CeWRN-1, with helicase domains. How these domains cooperate remains unclear. Here, we demonstrate the different contributions of MUT-7 and CeWRN-1 to 2...

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Bibliographic Details
Main Authors: Tsung-Yuan Hsu, Bo Zhang, Noelle D L'Etoile, Bi-Tzen Juang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-03-01
Series:eLife
Subjects:
neuronal plasticity
22G small RNA
werner syndrome protein
3'-5' exonuclease
Online Access:https://elifesciences.org/articles/62449

Internet

https://elifesciences.org/articles/62449

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