Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I study

Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I study

Abstract Background Adipose tissue-derived mesenchymal stem cells (AT-MSCs) offer potential as a therapeutic option for chronic discogenic low back pain (LBP) because of their immunomodulatory functions and capacity for cartilage differentiation. The goal of this study was to assess the safety and t...

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Bibliographic Details
Main Authors: Hemant Kumar, Doo-Hoe Ha, Eun-Jong Lee, Jun Hee Park, Jeong Hyun Shim, Tae-Keun Ahn, Kyoung-Tae Kim, Alexander E. Ropper, Seil Sohn, Chung-Hun Kim, Devang Kashyap Thakor, Soo-Hong Lee, In-Bo Han
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Stem Cell Research & Therapy
Subjects:
Intervertebral disc degeneration
Adipose-derived mesenchymal stem cells
Nucleus pulposus
Cell therapy
Hyaluronic acid
Online Access:http://link.springer.com/article/10.1186/s13287-017-0710-3

Internet

http://link.springer.com/article/10.1186/s13287-017-0710-3

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