Interleukin (IL)-4 Induces Leukocyte Infiltration In Vivo by an Indirect Mechanism

Interleukin (IL)-4 is a cytokine known mainly for its anti-inflammatory activity. Using the in vivo murine air pouch model, we found that IL-4 significantly increased the number of leukocytes after 9 hours of treatment, consisting mainly of neutrophil (60%) and monocytic (40%) cell populations. Usin...

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Bibliographic Details
Main Authors: Claude Ratthé, Jamila Ennaciri, David M. Garcês Gonçalves, Sonia Chiasson, Denis Girard
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2009/193970