Insula activity in resting-state differentiates bipolar from unipolar depression: a systematic review and meta-analysis

Abstract Symptomatic overlap of depressive episodes in bipolar disorder (BD) and major depressive disorder (MDD) is a major diagnostic and therapeutic problem. Mania in medical history remains the only reliable distinguishing marker which is problematic given that episodes of depression compared to...

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Bibliographic Details
Main Authors: Martin Pastrnak, Eva Simkova, Tomas Novak
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96319-2