PKA-Dependent Membrane Surface Recruitment of CI-AMPARs Is Crucial for BCP-Mediated Protection Against Post-acute Ischemic Stroke Cognitive Impairment

PKA-Dependent Membrane Surface Recruitment of CI-AMPARs Is Crucial for BCP-Mediated Protection Against Post-acute Ischemic Stroke Cognitive Impairment

Post-acute ischemic stroke cognitive impairment frequently occurs and seriously affects patients daily activities. Recruitment of GluA2-containing Ca2+-impermeable AMPA receptors (CI-AMPARs) to hippocampal synaptic membrane surfaces was shown to trigger synaptic plasticity. Currently, the effect of...

Full description

Bibliographic Details
Main Authors: Sha Chen, Yuchun Wang, Xuhui Wang, Meng He, Lu Zhang, Zhi Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Neurology
Subjects:
GluA2-containing Ca2+ -permeable AMPA receptors
β-caryophyllene
post-acute ischemic stroke
synaptic plasticity
long-term potentiation
long-term depression
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.566067/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2020.566067/full

Similar Items