A further investigation of combined mismatch repair and BRAFV600E mutation specific immunohistochemistry as a predictor of overall survival in colorectal carcinoma.

A further investigation of combined mismatch repair and BRAFV600E mutation specific immunohistochemistry as a predictor of overall survival in colorectal carcinoma.

Mutation specific immunohistochemistry (IHC) is a promising new technique to detect the presence of the BRAFV600E mutation in colorectal carcinoma (CRC). When performed in conjunction with mismatch repair (MMR) IHC, BRAFV600E IHC can help to further triage genetic testing for Lynch Syndrome. In a co...

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Bibliographic Details
Main Authors: Nathan Luey, Christopher W Toon, Loretta Sioson, Adele Clarkson, Nicole Watson, Carmen Cussigh, Andrew Kedziora, Stuart Pincott, Stephen Pillinger, Justin Evans, John Percy, Alexander Engel, Margaret Schnitzler, Anthony J Gill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4143358?pdf=render

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http://europepmc.org/articles/PMC4143358?pdf=render

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