Arabinosylated lipoarabinomannan skews Th2 phenotype towards Th1 during Leishmania infection by chromatin modification: involvement of MAPK signaling.

Arabinosylated lipoarabinomannan skews Th2 phenotype towards Th1 during Leishmania infection by chromatin modification: involvement of MAPK signaling.

The parasitic protozoan Leishmania donovani is the causative organism for visceral leishmaniasis (VL) which persists in the host macrophages by deactivating its signaling machinery resulting in a critical shift from proinflammatory (Th1) to an anti-inflammatory (Th2) response. The severity of this d...

Full description

Bibliographic Details
Main Authors: Parna Bhattacharya, Gaurav Gupta, Saikat Majumder, Anupam Adhikari, Sayantan Banerjee, Kuntal Halder, Suchandra Bhattacharya Majumdar, Moumita Ghosh, Shubho Chaudhuri, Syamal Roy, Subrata Majumdar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3173371?pdf=render

Internet

http://europepmc.org/articles/PMC3173371?pdf=render

Similar Items