Fumagillin-induced chromosome aberrations in mouse bone-marrow cells

The genotoxicity of fumagillin was evaluated assessing the mitotic index and chromosome aberrations in mouse bone-marrow cells. Mice were given fumagillin orally in doses 5, 10 and 20 mg/kg bw. All doses significantly (p<0.001) reduced the mitotic index. The medium and maximum doses led to si...

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Bibliographic Details
Main Authors: Stanimirović Z., Aleksić Nevenka, Kulić M., Maletić M.
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2010-01-01
Series:Archives of Biological Sciences
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2010/0354-46641001047S.pdf