Profound Chemopreventative Effects of a Hydrogen Sulfide-Releasing NSAID in the APCMin/+ Mouse Model of Intestinal Tumorigenesis.

Profound Chemopreventative Effects of a Hydrogen Sulfide-Releasing NSAID in the APCMin/+ Mouse Model of Intestinal Tumorigenesis.

Nonsteroidal anti-inflammatory drugs have been shown to reduce the incidence of gastrointestinal cancers, but the propensity of these drugs to cause ulcers and bleeding limits their use. H2S has been shown to be a powerful cytoprotective and anti-inflammatory substance in the digestive system. This...

Full description

Bibliographic Details
Main Authors: Mark Paul-Clark, Wagdi Elsheikh, Nicholas Kirkby, Melissa Chan, Pallavi Devchand, Terence A Agbor, Kyle L Flannigan, Charlotte Cheadle, Maxim Freydin, Angela Ianaro, Jane A Mitchell, John L Wallace
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4766010?pdf=render

Internet

http://europepmc.org/articles/PMC4766010?pdf=render

Similar Items