Plasma processing conditions substantially influence circulating microRNA biomarker levels.

Circulating, cell-free microRNAs (miRNAs) are promising candidate biomarkers, but optimal conditions for processing blood specimens for miRNA measurement remain to be established. Our previous work showed that the majority of plasma miRNAs are likely blood cell-derived. In the course of profiling lu...

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Bibliographic Details
Main Authors: Heather H Cheng, Hye Son Yi, Yeonju Kim, Evan M Kroh, Jason W Chien, Keith D Eaton, Marc T Goodman, Jonathan F Tait, Muneesh Tewari, Colin C Pritchard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3676411?pdf=render