Opposing Regulation of the EGF Receptor: A Molecular Switch Controlling Cytomegalovirus Latency and Replication.

Opposing Regulation of the EGF Receptor: A Molecular Switch Controlling Cytomegalovirus Latency and Replication.

Herpesviruses persist indefinitely in their host through complex and poorly defined interactions that mediate latent, chronic or productive states of infection. Human cytomegalovirus (CMV or HCMV), a ubiquitous β-herpesvirus, coordinates the expression of two viral genes, UL135 and UL138, which have...

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Bibliographic Details
Main Authors: Jason Buehler, Sebastian Zeltzer, Justin Reitsma, Alex Petrucelli, Mahadevaiah Umashankar, Mike Rak, Patricia Zagallo, Joyce Schroeder, Scott Terhune, Felicia Goodrum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4878804?pdf=render

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http://europepmc.org/articles/PMC4878804?pdf=render

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