IL18-containing 5-gene signature distinguishes histologically identical dermatomyositis and lupus erythematosus skin lesions

IL18-containing 5-gene signature distinguishes histologically identical dermatomyositis and lupus erythematosus skin lesions

Skin lesions in dermatomyositis (DM) are common, are frequently refractory, and have prognostic significance. Histologically, DM lesions appear similar to cutaneous lupus erythematosus (CLE) lesions and frequently cannot be differentiated. We thus compared the transcriptional profile of DM biopsies...

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Bibliographic Details
Main Authors: Lam C. Tsoi, Mehrnaz Gharaee-Kermani, Celine C. Berthier, Tori Nault, Grace A. Hile, Shannon N. Estadt, Matthew T. Patrick, Rachael Wasikowski, Allison C. Billi, Lori Lowe, Tamra J. Reed, Johann E. Gudjonsson, J. Michelle Kahlenberg
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-08-01
Series:JCI Insight
Subjects:
Autoimmunity
Dermatology
Online Access:https://doi.org/10.1172/jci.insight.139558

Internet

https://doi.org/10.1172/jci.insight.139558

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