Metformin Reverses Hashimoto’s Thyroiditis by Regulating Key Immune Events

BackgroundHashimoto’s thyroiditis (HT) is a common autoimmune disease characterized by high levels of thyroid peroxidase antibody (TPOAb) and thyroid globulin antibody (TgAb) as well as infiltration of lymphocytes in thyroid. In recent years, metformin has been proven to be effective in a variety of...

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Bibliographic Details
Main Authors: Xi Jia, Tianyu Zhai, Chunjie Qu, Jianjun Ye, Jing Zhao, Xuerong Liu, Jin-an Zhang, Qiaohui Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.685522/full