Inactivation of the Ecs ABC transporter of Staphylococcus aureus attenuates virulence by altering composition and function of bacterial wall.

Inactivation of the Ecs ABC transporter of Staphylococcus aureus attenuates virulence by altering composition and function of bacterial wall.

Ecs is an ATP-binding cassette (ABC) transporter present in aerobic and facultative anaerobic gram-positive Firmicutes. Inactivation of Bacillus subtilis Ecs causes pleiotropic changes in the bacterial phenotype including inhibition of intramembrane proteolysis. The molecule(s) transported by Ecs is...

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Bibliographic Details
Main Authors: Ing-Marie Jonsson, Jarmo T Juuti, Patrice François, Rana AlMajidi, Milla Pietiäinen, Myriam Girard, Catharina Lindholm, Manfred J Saller, Arnold J M Driessen, Pentti Kuusela, Maria Bokarewa, Jacques Schrenzel, Vesa P Kontinen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2996298?pdf=render

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http://europepmc.org/articles/PMC2996298?pdf=render

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