Lysophosphatidyl Choline Induced Demyelination in Rat Probed by Relaxation along a Fictitious Field in High Rank Rotating Frame

In this work a new MRI modality entitled Relaxation Along a Fictitious Field in the rotating frame of rank 4 (RAFF4) was evaluated in its ability to detect lower myelin content in lysophosphatidyl choline (LPC)-induced demyelinating lesions. The lesions were induced in two areas of the rat brain wit...

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Bibliographic Details
Main Authors: Lauri J. Lehto, Aloma A. Albors, Alejandra Sierra, Laura Tolppanen, Lynn E. Eberly, Silvia Mangia, Antti Nurmi, Shalom Michaeli, Olli Gröhn
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Neuroscience
Subjects:
DTI
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00433/full