Spatiotemporal Correlation of Epileptiform Activity and Gene Expression in vitro

Spatiotemporal Correlation of Epileptiform Activity and Gene Expression in vitro

Epileptiform activity alters gene expression in the central nervous system, a phenomenon that has been studied extensively in animal models. Here, we asked whether also in vitro models of seizures are in principle suitable to investigate changes in gene expression due to epileptiform activity and te...

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Bibliographic Details
Main Authors: Sophie Schlabitz, Laura Monni, Alienor Ragot, Matthias Dipper-Wawra, Julia Onken, Martin Holtkamp, Pawel Fidzinski
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
epileptiform activity in vitro
4-aminopyridine
intrinsic optical signals
gene expression
c-Fos
Icer
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.643763/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2021.643763/full

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