Defective Infiltration of Natural Killer Cells in MICA/B-Positive Renal Cell Carcinoma Involves β2-Integrin-Mediated Interaction

Defective Infiltration of Natural Killer Cells in MICA/B-Positive Renal Cell Carcinoma Involves β2-Integrin-Mediated Interaction

We have explored MICA/B expression and its relationship with innate inflammatory infiltrate in renal cell carcinoma (RCC). The expression of MICA/B, CD16, CD56, and CD68 in 140 RCC lesions contained in a tissue microarray (TMA) was investigated by immunohistochemistry. MICA/B gene and protein expre...

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Bibliographic Details
Main Authors: Giuseppe Sconocchia, Giulio Cesare Spagnoli, Domenico Del Principe, Soldano Ferrone, Maurizio Anselmi, Wachanan Wongsena, Valerio Cervelli, Elke Schultz-Thater, Stephen Wyler, Vincenza Carafa, Holger Moch, Luigi Terracciano, Luigi Tornillo
Format: Article
Language:English
Published: Elsevier 2009-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558609800183

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http://www.sciencedirect.com/science/article/pii/S1476558609800183

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