Can the use of older-generation beta-lactam antibiotics in livestock production over-select for beta-lactamases of greatest consequence for human medicine? An in vitro experimental model.

Though carbapenems are not licensed for use in food animals in the U.S., carbapenem resistance among Enterobacteriaceae has been identified in farm animals and their environments. The objective of our study was to determine the extent to which older-generation β-lactam antibiotics approved for use i...

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Bibliographic Details
Main Authors: Olanrewaju J Ogunrinu, Keri N Norman, Javier Vinasco, Gizem Levent, Sara D Lawhon, Virginia R Fajt, Victoria V Volkova, Tara Gaire, Toni L Poole, Kenneth J Genovese, Thomas E Wittum, H Morgan Scott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242195