Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression

Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression

Autosomal recessive primary microcephaly (MCPH) is a congenital disorder characterized by significantly reduced brain size and mental retardation. Nine genes are currently known to be associated with the condition, all of which encode centrosomal or spindle pole proteins. MCPH is associated with a r...

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Bibliographic Details
Main Authors: Claire Novorol, Janina Burkhardt, Kirstin J. Wood, Anila Iqbal, Claudio Roque, Nicola Coutts, Alexandra D. Almeida, Jie He, Christopher J. Wilkinson, William A. Harris
Format: Article
Language:English
Published: The Royal Society 2013-01-01
Series:Open Biology
Subjects:
zebrafish retina
microcephaly
stil
aspm
wdr62
odf2
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130065

Internet

https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130065

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