Novel Etiological and Therapeutic Strategies for Neurodiseases: Epigenetic Understanding of Gene–Environment Interactions

Epigenetics is a mechanism that regulates gene expression not depending on the underlying DNA sequence, but on the chemical modifications of DNA and histone proteins. Defects in the factors involved in epigenetic regulation cause congenital neurodevelopmental diseases, and thus, epigenetic regulatio...

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Bibliographic Details
Main Authors: Takeo Kubota, Kunio Miyake, Takae Hirasawa, Kaoru Nagai, Tsuyoshi Koide
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319309545