Natural Mutations Affect Structure and Function of gC1q Domain of Otolin-1
Otolin-1 is a scaffold protein of otoliths and otoconia, calcium carbonate biominerals from the inner ear. It contains a gC1q domain responsible for trimerization and binding of Ca<sup>2+</sup>. Knowledge of a structure–function relationship of gC1q domain of otolin-1 is crucial for unde...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-08-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/16/9085 |