A Computer Simulator for Assessing Different Challenges and Strategies of de Novo Sequence Assembly

A Computer Simulator for Assessing Different Challenges and Strategies of de Novo Sequence Assembly

This study presents a new computer program for assessing the effects of different factors and sequencing strategies on de novo sequence assembly. The program uses reads from actual sequencing studies or from simulations with a reference genome that may also be real or simulated. The simulated reads...

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Bibliographic Details
Main Authors: Bjarne Knudsen, Roald Forsberg, Michael M. Miyamoto
Format: Article
Language:English
Published: MDPI AG 2010-09-01
Series:Genes
Subjects:
assembly simulator
read simulator
de novo assembly
sequencing strategies
next generation sequencing
Online Access:http://www.mdpi.com/2073-4425/1/2/263/

Internet

http://www.mdpi.com/2073-4425/1/2/263/

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