The origins of specificity in polyketide synthase protein interactions.
Polyketides, a diverse group of heteropolymers with antibiotic and antitumor properties, are assembled in bacteria by multiprotein chains of modular polyketide synthase (PKS) proteins. Specific protein-protein interactions determine the order of proteins within a multiprotein chain, and thereby the...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-09-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC1994986?pdf=render |