MicroRNA-1179 suppresses the proliferation and enhances vincristine sensitivity of oral cancer cells via induction of apoptosis and modulation of MEK/ERK and PI3K/AKT signalling pathways

MicroRNA-1179 suppresses the proliferation and enhances vincristine sensitivity of oral cancer cells via induction of apoptosis and modulation of MEK/ERK and PI3K/AKT signalling pathways

Abstract The role of miR-1179 in the development of cancer has been proved by different studies. However, the expression profile and role of miR-1179 is yet to be explored in human oral cancer. Consistently, this study was undertaken to explore the molecular role of miR-1179 in regulation of the hum...

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Bibliographic Details
Main Authors: Yanmei Gao, Hanmei Xu, Tiemin Pu
Format: Article
Language:English
Published: SpringerOpen 2020-08-01
Series:AMB Express
Subjects:
Oral cancer
Micro RNA
Proliferation
Autophagy
Metastasis
Online Access:http://link.springer.com/article/10.1186/s13568-020-01082-8

Internet

http://link.springer.com/article/10.1186/s13568-020-01082-8

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