Mechanism of mitochondria-mediated PGC-1α in macrophage polarization

Mechanism of mitochondria-mediated PGC-1α in macrophage polarization

Objective To investigate the effect of knocking down peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) on the polarization in tumor-associated macrophages (TAMs). Methods Mouse peritoneal macrophages (PMs) were co-cultured with mouse mammary tumor cell line 4T1 for 24 h t...

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Bibliographic Details
Main Authors: JIN Xin, NI Tiangen, WANG Ning, LUO Haojun, LEI Youyang, MING Jia
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2019-01-01
Series:Di-san junyi daxue xuebao
Subjects:
breast cancer
tumor-associated macrophages
pgc-1α
mitochondrial function
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/201808139.htm

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http://aammt.tmmu.edu.cn/Upload/rhtml/201808139.htm

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