P-TEFb as A Promising Therapeutic Target

The positive transcription elongation factor b (P-TEFb) was first identified as a general factor that stimulates transcription elongation by RNA polymerase II (RNAPII), but soon afterwards it turned out to be an essential cellular co-factor of human immunodeficiency virus (HIV) transcription mediate...

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Bibliographic Details
Main Author: Koh Fujinaga
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
hiv
Online Access:https://www.mdpi.com/1420-3049/25/4/838