Bacterial delivery of the anti-tumor azurin-like protein Laz to glioblastoma cells

Bacterial delivery of the anti-tumor azurin-like protein Laz to glioblastoma cells

Abstract Salmonella typhimurium VNP-20009 (VNP) is a non-pathogenic attenuated strain, which, as a facultative anaerobe, preferentially accumulates in hypoxic regions of solid tumors. Here, VNP was utilized as a delivery vehicle of the anti-tumor protein Lipidated azurin, Laz, which is produced by t...

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Bibliographic Details
Main Authors: Manar Mansour, Shehab Ismail, Khaled Abou-Aisha
Format: Article
Language:English
Published: SpringerOpen 2020-03-01
Series:AMB Express
Subjects:
Hypoxia
Salmonella VNP20009
Azurin-like protein
Glioblastoma
Online Access:http://link.springer.com/article/10.1186/s13568-020-00995-8

Internet

http://link.springer.com/article/10.1186/s13568-020-00995-8

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