Effects of the single nucleotide polymorphism at MDM2 309 on breast cancer patients with/without BRCA1/2 mutations
<p>Abstract</p> <p>Background</p> <p>A germ line single nucleotide polymorphism (SNP) in the first intron of the gene encoding MDM2 at position 309, an important modulator of p53, has been described. BRCA1/2 mutation have been associated with increased rates of breast c...
Main Authors: | Sharon Nir, Kadouri Luna, Mendelson Susan, Hamburger Tamar, Nechushtan Hovav, Pikarsky Eli, Peretz Tamar |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-02-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/9/60 |
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